Strategies for Selecting Membrane Protein-Specific Antibodies using Phage Display with Cell-Based Panning
نویسندگان
چکیده
منابع مشابه
Strategies for Selecting Membrane Protein-Specific Antibodies using Phage Display with Cell-Based Panning
Membrane proteins are attractive targets for monoclonal antibody (mAb) discovery and development. Although several approved mAbs against membrane proteins have been isolated from phage antibody libraries, the process is challenging, as it requires the presentation of a correctly folded protein to screen the antibody library. Cell-based panning could represent the optimal method for antibody dis...
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ژورنال
عنوان ژورنال: Antibodies
سال: 2017
ISSN: 2073-4468
DOI: 10.3390/antib6030010